Effect of ethionine on tumor growth, carcass weight, and nonprotein amino acids in the liver of male and female Wistar rats.
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چکیده
Albert Tannenbaum. The Cancer Investigator: An Evaluation 547 Harry N. Bane, John T. Conrad, and George S. Tarnowski. Combination Therapy of Malig nant Tumors with Ionizing Radiations and Chemicals : A Review 551 Edward A. Murphy and Max S. Dunn. Effect of Ethionine on Tumor Growth, Carcass Weight, and Nonprotein Amino Acids in the Liver of Male and Female Wistar Rats 567 P. G. Stansly and D. S. Ramsey. Activity and Regulation of the Serum Trypsin-Inhibitor in Mice 572 Howard E. Skipper, Roland K. Robins, J. Richard Thomson, C. C. Cheng, R. Wallace Brockman, and Frank M. Schabel, Jr. Structure-Activity Relationships Observed on Screen ing a Series of Pyrazolopyrimidines against Experimental Neoplasms 579 F. N. Ghadially and Myron Gordon. A Localized Melanoma in a Hybrid Fish LebistesXMollienesia 597 Daniel M. Shapiro, L. S. Dietrich, and Maurice E. Shils. Quantitative Biochemical Differences between Tumor and Host as a Basis for Cancer Chemotherapy. V. Niacin and 6-Aminonicotinamide 600 Jean Scholler, John J. Bittner, and Frederick S. Philips. Chemotherapeutic Studies with Transplants of Spontaneous Mammary Tumors of Alice Growing in Various Hosts .... 605 J. Frank Henderson, G. A. LePage, and Forde A. Mclver. Observations on the Action of Azaserine in Mammalian Tissues 609 Alice Andrews Greene and Frances L. Haven. Cytochrome Oxidase in the Liver of the Rat Bearing Walker Carcinoma 256 613 William A. Cassel. Multiplication of Influenza Virus in the Ehrlich Ascites Carcinoma . . . 618 Darrell N. Ward and James D. Spain. Protein-bound Azo Dye in the Liver of Hypophysectomized Rats 623 A. H. Conney, R. R. Brown, J. A. Miller, and E. C. Miller. The Metabolism of Methylated Aminoazo Dyes. VI. Intracellular Distribution and Properties of the Demethylase System . . 628 Announcement 634
منابع مشابه
Effect of Ethionine on Tumor Growth, Carcass Weight, and Nonprotein Amino Acids in the Liver of Male and Female Wistar Rats*
It has been shown in the authors' laboratory that a low level of DL-ethionine, alone or in combi nation with certain amino acids, decreased carcass weight and inhibited the growth of Sarcoma R-l in male Wistar rats (3). The degree of tumor inhi bition, however, was not as great as that observed with comparable levels of ethionine administered to Long-Evans rats bearing the Jensen sarcoma or the...
متن کاملEffect of ethionine alone or with amino acids on tumor growth, carcass weight, and nonprotein amino acids in rat liver.
Studies have been made previously on the ef fect of ethionine on the free amino acids in the livers of tumorous and nontumorous rats of the Long-Evans (6, 8), Sprague-Dawley (13), and Wistar (9) strains. Attempts at dual blocking, with pairs of antimetabolites, have also been re ported (12). The observation that certain amino acids may function as antimetabolites in inhibiting tumor growth (3, ...
متن کاملEffects of age, sex, strain, and methionine analogs on the nonprotein amino acids in the liver of normal and tumorous rats.
that ethionine was a more effective inhibitor of the Jensen sarcoma or the U.C.L.A. fibrosarcoma in Long-Evans strain rats than of Sarcoma R-l in Wistar strain rats (2, 10), and that the effect of this antimetabolite was greater in female than in male Wistar rats (15). It is believed that these variations in inhibition reflect differences in the host animals rather than in the tumors, since it ...
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عنوان ژورنال:
- Cancer research
دوره 17 6 شماره
صفحات -
تاریخ انتشار 1957